Dustin Kapraun attained degrees in mathematics (B.S., 1998), physics (M.S., 2002), and applied mathematics (Ph.D., 2014), all from North Carolina State University. After finishing the Ph.D., he completed two postdoctoral research appointments at the U.S. Environmental Protection Agency (EPA) National Center for Computational Toxicology, during which he developed physiologically based pharmacokinetic (PBPK) models for human pregnancy and data mining methods for identifying prevalent combinations of chemicals in humans. In 2017, Dr. Kapraun joined the EPA National Center for Environmental Assessment (NCEA) as a Physical Scientist specializing in PBPK modeling for chemical risk assessment applications. He currently works at the EPA Center for Public Health and Environmental Assessment (CPHEA), where he continues to develop and apply PBPK and other mathematical and statistical models to support chemical risk assessments and serves as a Co-Chair of the CPHEA Pharmacokinetics Workgroup (PKWG). Dr. Kapraun still has a passion for education, which he satisfies by mentoring postdoctoral researchers in quantitative risk assessment methods and leading workshops and training sessions on PBPK modeling and related topics. In this talk, Dr. Kapraun will describe a variety of interesting problems he has encountered during his time at EPA and how he and his colleagues have applied mathematical and computational methods to generate solutions.