Global sensitivity analysis (GSA) offers a flexible framework for understanding the structural importance of uncertain parameters in mathematical models. This dissertation focuses on forward and inverse problems arising in uncertainty quantification and the computation of Sobol’ indices, measures of variance-based sensitivity. The models involved in these prob- lems are often computationally expensive to evaluate. Sensitivity…

Reduced-order models (ROMs) are a critical tool for sensitivity analysis, parameter inference, and uncertainty quantification where high-fidelity models would be computationally intractable. Galerkin POD-ROMs are one particular class of ROMs which project high-fidelity model equations onto a set of model solutions to construct ROMs retaining original model parameters and physics, enabling accurate sensitivity analysis, parameter inference,…