John Lowengrub, University of California, Irvine, BioDDFT: A hybrid continuum-discrete mechanical collective cell model
SAS 4201The regulation of cell division, cell sizes and cell arrangements is central to tissue morphogenesis. To study these processes, we develop a mechanistic hybrid continuum-discrete mathematical model of cell dynamics that has advantages over previous approaches. This model borrows ideas from statistical physics, materials science and applied mathematics and follows the framework of dynamic density…