Boris Gutkin, École Normale Supérieure, Paris, “Dynamics of dopamine neuron firing in normal and drug-modulated conditions”
Cox 306Dopaminergic neurons in the ventral tegmental area play a key role in signalling motivational information. Modulation of this signalling by drugs is also key to the development of addiction. These neurons have several firing modes ranging from periodic low frequency activity to higher frequency bursts. In vitro, intrinsically generated bursts are seen, while in vivo…